What is Tadalafil?

Tadalafil is a prescribed medicine that is known for dealing with male impotence issue like Erectile Dysfunction or repeated penile failure in men. The trusted component belongs to a class of medicine called PDE5 inhibitors. Medicine is known for working by enhancing flow of blood in the penile, which helps to gain stiffer erection that lasts for longer time. It works on the chain of reactions within the penile during sexual arousal, when corpus cavernosa in the male’s penile is filled with blood. This mechanism of medicine results in perfect erection for longer time.

Following are specification of Tadalafil component:

Formula: C₂₂H₁₉N₃O₄

Systematic Name: (6R-trans)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1', 2':1,6] pyrido [3,4-b] indole-1,4 - dione

Molecular Weight: 389.404 g/mol

Erection occurs when penile is filled with proper amount of blood. Action mechanism of this component occurs when blood vessels that supply blood to penile expands (dilate).

When man is sexually aroused, nitric oxide is released into penile. This nitric oxide sensationally triggers a chain of reactions that further makes an enzyme called guanylate cyclase produce cyclic guanosine monophosphate (cGMP). This enzyme cGMP regulates contraction and dilation (expansion) blood vessels to carry blood from and within the penile. This chemical reaction makes vessels in penile to dilate, while those removing blood from the penile contract, resulting in erection that is stiffer and long lasting.

Enzyme Phosphodiesterase-5 (PDE5) breaks down cGMP. When cGMP is destroyed blood vessels return to their normal size, effectively ending erection of penile. Tadalafil inhibits PDE5 degradation of cGMP, i.e. it prolongs cGMP's function.

Tadalista medicine is available in various strengths of 2.5mg, 5mg, 10mg and 20mg. Medicine has to be consumed about 30 minutes to one hour before intercourse. Avoid intake of medicine for more than one tablet a week. Tadalafil composed medicine works only when consumed in presence of complete sexual arousal.